Continuous dry granulation by roller compaction is a well-established process in pharmaceutical, chemical and life science industry, targeted to increase the flow ability of a powder or powder blend to enable fast and homogeneous filling of a tablet press. Challenge is to produce tablets of constant weight and sufficient strength, while maintaining an even distribution of the Active Pharmaceutical Ingredients (API). This is achieved by roller compaction for a wide range of products and without need of additional ingredients such as binders, moisture or lubricants. Dry granulation by roller compaction is used to eliminate dust, increase the bulk density, reduce the storage volume, improve handling and manipulate the dissolution properties.
- Accurate and precise dosage.
- Reduction in dust formation at the workplace.
- Positive influence to dispersion and solubility characteristics.
- Homogenous distribution
Using a suitable feed-in system, powder is routed through a horizontal screw feeding section. This provide the product precisely dosed, constantly and accurately to the rollers.2. Compaction
Powder is compacted between two rollers to a homogenous solid flake, whose bulk density is significantly higher. Air which is displaced during compaction, must be allowed to leave the process properly.3. Granulation
Flakes produced through the compaction process, are granulated using a suitable single or multistage granulation system. Granules are created to the defined size.VERTICAL ROLLER ARRANGEMENTS:
Vertical roller arrangement allows greater control of feed flow without the influences of gravity. Moreover, side seal losses can be separated from the compacted material and can be added back to the raw material, if required. This leads to a minimization of fine material in the finished product without having any negative influence on the consistency and composition of the batch.COMBO-FEEDER:
With the Optimisation of the feeding system known as Combo-Feeder, the air, which is displaced during the compaction process, is allowed to escape properly through a second chamber of the feed hopper without disruption of the feed, thus leading to a uniform feed of raw material into the rollers. Furthermore, the second chamber can be used to recycle undersize and oversize granule, which can be homogeneously added to the raw material, if required. In addition, the feeding unit can be assisted by using a vacuum system, which provides a minimal product layer on the inside of the screw housing. This greatly improves the processing of fluidizing products with low bulk density.TWO-STAGE GRANULATION IN DIAGONAL-DESIGN:
Rotor screen granulators are commonly used in the chemical, food and pharmaceutical industry for sizing of soft to medium hard products. The Rotor-Fine-Granulators consists of a rotor with vertical rotor bars and screen mesh through which the granulate is pushed by the rotor. Incoming flakes undergoes further pre-crushing, before it is compressed into the working zone. In this zone the particle size is reduced by pushing the material through the screen.
|Working Capacity (Output)
|15 To 80 Kg/hr*
|30 To 250 Kg/hr*
|60 To 300 Kg/hr*
|60 To 400 Kg/hr*
|Ø150 X 70 W
|Ø200 X 100 W
|Ø250 X 150 W
|Ø250 X 200 W
|3 To 29 Rpm
|6 To 25 Rpm
|6 To 22 Rpm
|6 To 20 Rpm
|Feed Screw Speed (Horizontal)VFD
|Feed Screw Speed (Vertical)VFD
|Roll Max Force
- Working volume depends on material characteristic and product bulk density.
- Company reserves the right to modify technical speciﬁcations.